Rangers suffered an agonising penalty shootout defeat in their fifth European final as Eintracht Frankfurt triumphed in an absorbing Europa League decider.
Rafael Borre crashed in the decisive spot-kick after Aaron Ramsey was denied just moments earlier in front of a colossal Rangers support in the Ramon Sanchez Pizjuan Stadium.
Those fans had been euphoric when the Scots took the lead through Joe Aribo's ice-cool second-half finish in the sweltering cauldron in Seville.
However, Borre detonated raucous scenes in a jam-packed Eintracht end 12 minutes later as he steered in a soft equaliser to send this energy-sapping contest to extra time and penalties.
And Rangers' players crumpled to their feet as the 11th-placed side in the Bundesliga prevailed in the shootout, executing five composed penalties to claim their second European trophy and a place in next season's Champions League group stages.
Under a humid Spanish sky, this one seemed written in the stars for Rangers. Their only previous win in Spain came in the 1972 European Cup Winners' Cup final, when the Barca Bears stormed past Dynamo Moscow for their first European trophy.
The pilgrimage to Seville in the hope of repeating the feat of Jardine, Stein, Greig and Johnstone was a long and arduous one.
It started in the Champions League qualifiers against Malmo last summer for the players and for the men, women and children who spilled into Seville from the four corners of the world to support them. This was their chance to see the class of 2022 become immortal, and over 100,000 made the trip in hope and expectation.
Well before kick-off, the ground swarmed with light blue. An original allocation of just under 9,500 looked fanciful when the sides entered to a cacophony so loud it could wake the dead.
Around two thirds of the stadium swayed, rocked and roared with Scots, leaving their German counterparts and their flag display looking a little humble. Frankfurt were brighter on the pitch, though. They were quick and aggressive, while Rangers appeared nervous.
James Tavernier had flashes on the right, but the intensity which stung Dortmund, Braga and Leipzig was missing. Ansgar Knauff drew a tremendous save from Allan McGregor, then Djibril Sow went close as the German fans raised the noise level in appreciation.
Rangers retaliated through Aribo. Time stopped dead as he wrapped his foot around the ball on the edge of the area. The sight of it flashing by the far post by a foot will race through his mind for a while yet.
Both teams exchanged jabs before Rangers, who survived a VAR penalty scare courtesy of a rash Connor Goldson lunge, landed an incredible blow.
Football may be a game of tactics, money and talent, but at times it can offer up the inexplicable. There is little explanation for Sow's flopped header towards his own goal. Or the stumble from Tuta which allowed Aribo to bustle in on goal.
The Rangers fans held their breath before bursting into life as the ball hit the net after a low finish. Giovanni van Bronckhorst punched the air and roared into the night sky.
Rangers were in control now and that will make the anguish of defeat hurt so much more. The slap in the face came just 12 minutes later, Borre stealing in between Connor Goldson and Calvin Bassey to force home a teasing but cheap cross.
Extra time beckoned as Eintracht went for a knockout blow, but Rangers - and their support - roused themselves and should have won it two minutes before penalties.
Substitute Kemar Roofe charged to the goal-line and his deflected cutback fell for Ryan Kent with the goal gaping, but Kevin Trapp's save expelled a giant gasp from the crowd. Tavernier's arcing free-kick in the dying seconds was also palmed away.
Ramsey was a late edition to the match with penalties in mind. The on-loan Juventus man had the opportunity to make it 4-3 in the shootout after Tavernier, Steven Davis and Scott Arfield slotted Rangers' first three kicks, but the Welsh midfielder's tame effort down the middle was whacked away by Trapp.
It would be the only miss of the shootout, as Rangers' marathon run in Europe came to the most agonising of ends in a flurry of white bedlam.