Phil Ofosu-Ayeh and Ebenezer Assifuah have an opportunity to make their first competitive appearance for the Black Stars when Ghana face Comoros in a two-leg FIFA World Cup qualifier, beginning November 13.
The duo, alongside surprise inclusions; Wa All Stars goalie, Richard Ofori and West Africa Football Academy winger, Samuel Tetteh, were named in Coach Avram Grant's 23-man squad for the two-leg fixtures on November 13 and 17 in the Comoros and the Baba Yara Stadium in Kumasi respectively.
Eintracht Braunschweig right-back, Ofosu-Ayeh, 24, appears to have earned his call-up on the back of his debut appearance for the Stars against Canada, as well as his performances for his club side in their quest for Bundesliga promotion.
WAFA's Tetteh, 19, is also rewarded for starring with the Black Satellites last June at the FIFA U-20 World Cup. He was also a part of the home-based Black Stars team that failed to qualify for the 2016 CHAN after losing to Cote d'Ivoire.
Former Liberty Professionals attacker, Assifuah, is also rewarded for his consistency with FC Sion in the Swiss Super League where he has featured in all 14 of his club's games. He also scored a memorable goal at Anfield last month when Sion held Liverpool to a 1-1 draw.
Meanwhile, Grant also recalled his skipper Asamoah Gyan and vice skipper Andre Ayew who missed last month's friendly against Canada through injury.
Below is the full squad:
Goalkeepers: Razak Braimah (Cordoba, Spain), Fatau Dauda (AshGold), Richard Ofori (Wa All Stars)
Defenders: Harrison Afful (Columbus Crew, USA), (Phil Ofosu-Ayeh, Eintracht Braunschweig, Germany), Jeffery Schlupp (Leicester City, England), Baba Rahman (Chelsea, England), John Boye (Sivasspor, Turkey), Jonathan Mensah (Evian, France), Gyimah Edwin (Orlando Pirates, South Africa), Daniel Amartey, (FC Copenhagen, Denmark)
Midfielders: Rabiu Mohammed (Krasnodar, Russia), Emmanuel Agyemang-Badu (Udinese, Italy), Afriyie Acquah (Torino, Italy), Solomon Asante (T.P. Mazembe, DR Congo), Samuel Tetteh (WAFA), Andre Ayew (Swansea City, UK), Mubarak Wakaso (Las Palmas, Spain)
Strikers: Asamoah Gyan (SIPG Shanghai, China), Jordan Ayew (Aston Villa, England), Abdul-Majeed Waris (Lorient, France) Ebenezer Assifuah (Sion, Switzerland), David Accam (Chicago Fire, USA).