Egypt has told the Turkish ambassador to leave the country and downgraded relations between the two countries.
It follows remarks by Turkish Prime Minister Recep Tayyip Erdogan that Cairo deemed "provocative".
Egypt's foreign ministry said relations with Ankara would be lowered to charge d'affaires, blaming Turkey's continued "interference" in its internal affairs.
Turkey has been a vocal critic of the military overthrow of Islamist President Mohammed Morsi in July.
Mr Morsi, who is in prison awaiting trial, has denounced as illegitimate the court that is trying him on charges of inciting murder and violence.
He is one of thousands of Muslim Brotherhood members that have been detained in a crackdown the interim authorities have portrayed as a struggle against "terrorism".
Hundreds of people have also been killed in clashes with security forces.
Bitter row
Cairo's decision to expel Ambassador Huseyin Avni Botsali comes a day after Mr Erdogan called for the release of Mr Morsi.
The Turkish premier again condemned the violent dispersal of pro-Morsi protesters in August by Egyptian security forces.
