Black Stars coach, Kwasi Appiah has made four changes in his squad that drew goalless draw with Cameroon for the last group game against Guinea-Bissau on Tuesday in Suez.
Defender Joseph Aidoo will make his AFCON bow in the absence of suspended Kassim Nuhu, while John Boye returns from suspension following the red card he picked in the opening group match against Benin to replace injured Jonathan Mensah.
Following deputy captain, Kwadwo Asamoah's below standard performance against Cameroun, the deputy captain has been sacrificed for Kwabena Owusu to partner Jordan Ayew upfront as the Black Stars need a win to qualify to the next stage of the competition.
Richard Ofori (GK), Andy Yiadom, Baba Rahman, Joseph Aidoo
John Boye, Mubarak Wakaso, Thomas Partey, Andre Dede Ayew (C), Kwabena Owusu, Samuel Owusu and Jordan Ayew.